α-Synuclein vaccination modulates regulatory T cell activation and microglia in the absence of brain pathology

BACKGROUND: Passive and active immunization with α-synuclein has been shown to be neuroprotective in animal models of Parkinson’s disease. We have previously shown that vaccination with α-synuclein, long before α-synuclein-induced brain pathology, prevents striatal degeneration by inducing regulator...

Descripción completa

Detalles Bibliográficos
Autores principales: Christiansen, Josefine R., Olesen, Mads N., Otzen, Daniel E., Romero-Ramos, Marina, Sanchez-Guajardo, Vanesa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825077/
https://www.ncbi.nlm.nih.gov/pubmed/27055651
http://dx.doi.org/10.1186/s12974-016-0532-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825077/
https://www.ncbi.nlm.nih.gov/pubmed/27055651
http://dx.doi.org/10.1186/s12974-016-0532-8

Ejemplares similares