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α-Synuclein vaccination modulates regulatory T cell activation and microglia in the absence of brain pathology

BACKGROUND: Passive and active immunization with α-synuclein has been shown to be neuroprotective in animal models of Parkinson’s disease. We have previously shown that vaccination with α-synuclein, long before α-synuclein-induced brain pathology, prevents striatal degeneration by inducing regulator...

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Detalles Bibliográficos
Autores principales:	Christiansen, Josefine R., Olesen, Mads N., Otzen, Daniel E., Romero-Ramos, Marina, Sanchez-Guajardo, Vanesa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825077/ https://www.ncbi.nlm.nih.gov/pubmed/27055651 http://dx.doi.org/10.1186/s12974-016-0532-8

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