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An FGFR1-SPRY2 Signaling Axis Limits Basal Cell Proliferation in the Steady-State Airway Epithelium

The steady-state airway epithelium has a low rate of stem cell turnover but can nevertheless mount a rapid proliferative response following injury. This suggests a mechanism to restrain proliferation at steady state. One such mechanism has been identified in skeletal muscle in which pro-proliferativ...

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Detalles Bibliográficos
Autores principales: Balasooriya, Gayan I., Johnson, Jo-Anne, Basson, M. Albert, Rawlins, Emma L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825408/
https://www.ncbi.nlm.nih.gov/pubmed/27046834
http://dx.doi.org/10.1016/j.devcel.2016.03.001