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Network-Based Analysis of eQTL Data to Prioritize Driver Mutations

In clonal systems, interpreting driver genes in terms of molecular networks helps understanding how these drivers elicit an adaptive phenotype. Obtaining such a network-based understanding depends on the correct identification of driver genes. In clonal systems, independent evolved lines can acquire...

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Detalles Bibliográficos
Autores principales: De Maeyer, Dries, Weytjens, Bram, De Raedt, Luc, Marchal, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825419/
https://www.ncbi.nlm.nih.gov/pubmed/26802430
http://dx.doi.org/10.1093/gbe/evw010