Aspartate facilitates mitochondrial function, growth arrest and survival during doxorubicin exposure

Genomic screens of doxorubicin toxicity in S. cerevisiae have identified numerous mutants in amino acid and carbon metabolism which express increased doxorubicin sensitivity. This work examines the effect of amino acid metabolism on doxorubicin toxicity. S. cerevisiae were treated with doxorubicin i...

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Detalles Bibliográficos
Autores principales: Dornfeld, Ken, Madden, Michael, Skildum, Andrew, Wallace, Kendall B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825578/
https://www.ncbi.nlm.nih.gov/pubmed/26317891
http://dx.doi.org/10.1080/15384101.2015.1087619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825578/
https://www.ncbi.nlm.nih.gov/pubmed/26317891
http://dx.doi.org/10.1080/15384101.2015.1087619

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