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Aspartate facilitates mitochondrial function, growth arrest and survival during doxorubicin exposure
Genomic screens of doxorubicin toxicity in S. cerevisiae have identified numerous mutants in amino acid and carbon metabolism which express increased doxorubicin sensitivity. This work examines the effect of amino acid metabolism on doxorubicin toxicity. S. cerevisiae were treated with doxorubicin i...
Autores principales: | Dornfeld, Ken, Madden, Michael, Skildum, Andrew, Wallace, Kendall B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825578/ https://www.ncbi.nlm.nih.gov/pubmed/26317891 http://dx.doi.org/10.1080/15384101.2015.1087619 |
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