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p53-mediated control of gene expression via mRNA translation during Endoplasmic Reticulum stress

p53 is activated by different stress and damage pathways and regulates cell biological responses including cell cycle arrest, repair pathways, apoptosis and senescence. Following DNA damage, the levels of p53 increase and via binding to target gene promoters, p53 induces expression of multiple genes...

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Detalles Bibliográficos
Autores principales: López, Ignacio, Tournillon, Anne-Sophie, Nylander, Karin, Fåhraeus, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825612/
https://www.ncbi.nlm.nih.gov/pubmed/26397130
http://dx.doi.org/10.1080/15384101.2015.1090066