Hypoxia-induced DNp73 stabilization regulates Vegf-A expression and tumor angiogenesis similar to TAp73

P73, the homolog of p53, exists in 2 major forms: either as a pro-apoptotic TAp73 or an amino-terminally truncated DNp73, the latter lacking the first transactivation domain. While TAp73s tumor suppressive functions have been established, DNp73 is an anti-apoptotic protein conferring chemoresistance...

Descripción completa

Detalles Bibliográficos
Autores principales: Dulloo, Iqbal, Hooi, Phang Beng, Sabapathy, Kanaga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Extra View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825702/
https://www.ncbi.nlm.nih.gov/pubmed/26267146
http://dx.doi.org/10.1080/15384101.2015.1078038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825702/
https://www.ncbi.nlm.nih.gov/pubmed/26267146
http://dx.doi.org/10.1080/15384101.2015.1078038

Ejemplares similares