Anti-protozoal and anti-bacterial antibiotics that inhibit protein synthesis kill cancer subtypes enriched for stem cell-like properties

Key players in translational regulation such as ribosomes might represent powerful, but hitherto largely unexplored, targets to eliminate drug-refractory cancer stem cells (CSCs). A recent study by the Lisanti group has documented how puromycin, an old antibiotic derived from Streptomyces alboniger...

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Detalles Bibliográficos
Autores principales: Cuyàs, Elisabet, Martin-Castillo, Begoña, Corominas-Faja, Bruna, Massaguer, Anna, Bosch-Barrera, Joaquim, Menendez, Javier A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825717/
https://www.ncbi.nlm.nih.gov/pubmed/25970790
http://dx.doi.org/10.1080/15384101.2015.1044173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825717/
https://www.ncbi.nlm.nih.gov/pubmed/25970790
http://dx.doi.org/10.1080/15384101.2015.1044173

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