Amyloid Beta-Mediated Hypomethylation of Heme Oxygenase 1 Correlates with Cognitive Impairment in Alzheimer’s Disease

To identify epigenetically regulated genes involved in the pathogenesis of Alzheimer’s disease (AD) we analyzed global mRNA expression and methylation profiles in amyloid precursor protein (APP)-Swedish mutant-expressing AD model cells, H4-sw and selected heme oxygenase-1 (HMOX1), which is associate...

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Detalles Bibliográficos
Autores principales: Sung, Hye Youn, Choi, Byung-Ok, Jeong, Jee Hyang, Kong, Kyoung Ae, Hwang, Jinha, Ahn, Jung-Hyuck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825942/
https://www.ncbi.nlm.nih.gov/pubmed/27058954
http://dx.doi.org/10.1371/journal.pone.0153156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825942/
https://www.ncbi.nlm.nih.gov/pubmed/27058954
http://dx.doi.org/10.1371/journal.pone.0153156

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