Single calcium channel domain gating of synaptic vesicle fusion at fast synapses; analysis by graphic modeling

At fast-transmitting presynaptic terminals Ca(2+) enter through voltage gated calcium channels (CaVs) and bind to a synaptic vesicle (SV) -associated calcium sensor (SV-sensor) to gate fusion and discharge. An open CaV generates a high-concentration plume, or nanodomain of Ca(2+) that dissipates pre...

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Detalles Bibliográficos
Autor principal: Stanley, Elise F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826128/
https://www.ncbi.nlm.nih.gov/pubmed/26457441
http://dx.doi.org/10.1080/19336950.2015.1098793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826128/
https://www.ncbi.nlm.nih.gov/pubmed/26457441
http://dx.doi.org/10.1080/19336950.2015.1098793

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