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A chemical screen to identify inducers of the mitochondrial unfolded protein response in C. elegans
We previously showed that inhibition of the mevalonate pathway in C. elegans causes inhibition of protein prenylation, developmental arrest and lethality. We also showed that constitutive activation of the mitochondrial unfolded protein response, UPR(mt), is an effective way for C. elegans to become...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826155/ https://www.ncbi.nlm.nih.gov/pubmed/27123370 http://dx.doi.org/10.1080/21624054.2015.1096490 |