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Blocking the survival of the nastiest by HSP90 inhibition

It is now recognised that genetic, epigenetic and phenotypic heterogeneity within individual human cancers is responsible for therapeutic resistance – knowledge that is having a profound impact on current thinking and experimentation. There has been concern that molecularly targeted therapy is doome...

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Detalles Bibliográficos
Autores principales: Workman, Paul, Clarke, Paul A., Al-Lazikani, Bissan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826159/
https://www.ncbi.nlm.nih.gov/pubmed/26820296
http://dx.doi.org/10.18632/oncotarget.6971