DNA demethylation caused by 5-Aza-2′-deoxycytidine induces mitotic alterations and aneuploidy

Aneuploidy, the unbalanced number of chromosomes in a cell, is considered a prevalent form of genetic instability and is largely acknowledged as a condition implicated in tumorigenesis. Epigenetic alterations like DNA hypomethylation have been correlated with cancer initiation/progression. Furthermo...

Descripción completa

Detalles Bibliográficos
Autores principales: Costa, Giuseppe, Barra, Viviana, Lentini, Laura, Cilluffo, Danilo, Di Leonardo, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Chromosome
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826165/
https://www.ncbi.nlm.nih.gov/pubmed/26771138
http://dx.doi.org/10.18632/oncotarget.6897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826165/
https://www.ncbi.nlm.nih.gov/pubmed/26771138
http://dx.doi.org/10.18632/oncotarget.6897

Ejemplares similares