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DNA demethylation caused by 5-Aza-2′-deoxycytidine induces mitotic alterations and aneuploidy

Aneuploidy, the unbalanced number of chromosomes in a cell, is considered a prevalent form of genetic instability and is largely acknowledged as a condition implicated in tumorigenesis. Epigenetic alterations like DNA hypomethylation have been correlated with cancer initiation/progression. Furthermo...

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Detalles Bibliográficos
Autores principales:	Costa, Giuseppe, Barra, Viviana, Lentini, Laura, Cilluffo, Danilo, Di Leonardo, Aldo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper: Chromosome
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826165/ https://www.ncbi.nlm.nih.gov/pubmed/26771138 http://dx.doi.org/10.18632/oncotarget.6897

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