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Carnitine palmitoyltransferase 1A functions to repress FoxO transcription factors to allow cell cycle progression in ovarian cancer

Cancer cells rely on hyperactive de novo lipid synthesis for maintaining malignancy. Recent studies suggest involvement in cancer of fatty acid oxidation, a process functionally opposite to lipogenesis. A mechanistic link from lipid catabolism to oncogenic processes is yet to be established. Carniti...

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Detalles Bibliográficos
Autores principales: Shao, Huanjie, Mohamed, Esraa M., Xu, Guoyan G., Waters, Michael, Jing, Kai, Ma, Yibao, Zhang, Yan, Spiegel, Sarah, Idowu, Michael O., Fang, Xianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826173/
https://www.ncbi.nlm.nih.gov/pubmed/26716645
http://dx.doi.org/10.18632/oncotarget.6757