Cargando…

Carnitine palmitoyltransferase 1A functions to repress FoxO transcription factors to allow cell cycle progression in ovarian cancer

Cancer cells rely on hyperactive de novo lipid synthesis for maintaining malignancy. Recent studies suggest involvement in cancer of fatty acid oxidation, a process functionally opposite to lipogenesis. A mechanistic link from lipid catabolism to oncogenic processes is yet to be established. Carniti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shao, Huanjie, Mohamed, Esraa M., Xu, Guoyan G., Waters, Michael, Jing, Kai, Ma, Yibao, Zhang, Yan, Spiegel, Sarah, Idowu, Michael O., Fang, Xianjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826173/ https://www.ncbi.nlm.nih.gov/pubmed/26716645 http://dx.doi.org/10.18632/oncotarget.6757

Ejemplares similares

Carnitine palmitoyltransferase 1A promotes mitochondrial fission by enhancing MFF succinylation in ovarian cancer
por: Zhu, Yaqin, et al.
Publicado: (2023)

Severe rhabdomyolysis in homozygote carnitine palmitoyltransferase II deficiency
por: Schnedl, Wolfgang J., et al.
Publicado: (2020)

Carnitine palmitoyltransferase 2 deficiency, malignant hyperthermia and anesthesia
por: Glauber, Violeta, et al.
Publicado: (2014)

Stabilization of the thermolabile variant S113L of carnitine palmitoyltransferase II
por: Motlagh, Leila, et al.
Publicado: (2016)

Carnitine palmitoyltransferase 1C contributes to progressive cellular senescence
por: Wang, Yongtao, et al.
Publicado: (2020)

Carnitine Palmitoyltransferase 1A Has a Lysine Succinyltransferase Activity
por: Kurmi, Kiran, et al.
Publicado: (2018)

Carnitine Palmitoyltransferase 1 Regulates Prostate Cancer Growth under Hypoxia
por: Rios-Colon, Leslimar, et al.
Publicado: (2021)

PSUN63 Approach to hyperlipidemia management in Carnitine Palmitoyltransferase II deficiency
por: Anbari, Raghda A, et al.
Publicado: (2022)

Polymerase independent repression of FoxO1 transcription by sequence-specific PARP1 binding to FoxO1 promoter
por: Tian, Yu-Nan, et al.
Publicado: (2020)

A causal link from ALK to hexokinase II overexpression and hyperactive glycolysis in EML4-ALK-positive lung cancer
por: Ma, Yibao, et al.
Publicado: (2016)

Fatty acid oxidation and carnitine palmitoyltransferase I: emerging therapeutic targets in cancer
por: Qu, Q, et al.
Publicado: (2016)

Muscle Carnitine Palmitoyltransferase II (CPT II) Deficiency: A Conceptual Approach
por: Joshi, Pushpa Raj, et al.
Publicado: (2020)

Carnitine Palmitoyltransferase System: A New Target for Anti-Inflammatory and Anticancer Therapy?
por: Wang, Muyun, et al.
Publicado: (2021)

A Case of Carnitine Palmitoyltransferase II Deficiency in Bahrain With a Novel Mutation
por: Alsahlawi, Zahra, et al.
Publicado: (2022)

From recurrent rhabdomyolysis in a young adult to carnitine palmitoyltransferase II deficiency
por: Marques, Cristina, et al.
Publicado: (2023)

Isothermal titration calorimetry with micelles: Thermodynamics of inhibitor binding to carnitine palmitoyltransferase 2 membrane protein()
por: Perspicace, Samantha, et al.
Publicado: (2013)

Abbreviated Half-Lives and Impaired Fuel Utilization in Carnitine Palmitoyltransferase II Variant Fibroblasts
por: Yao, Min, et al.
Publicado: (2015)

Muscle Carnitine Palmitoyltransferase II Deficiency: A Review of Enzymatic Controversy and Clinical Features
por: Lehmann, Diana, et al.
Publicado: (2017)

Carnitine Palmitoyltransferase II Deficiency (CPT II) Followed By Rhabdomyolysis and Acute Kidney Injury
por: Gjorgjievski, Nikola, et al.
Publicado: (2018)

Lysophosphatidic Acid Up-Regulates Hexokinase II and Glycolysis to Promote Proliferation of Ovarian Cancer Cells()
por: Mukherjee, Abir, et al.
Publicado: (2015)

Casticin induces ovarian cancer cell apoptosis by repressing FoxM1 through the activation of FOXO3a
por: JIANG, LING, et al.
Publicado: (2013)

Inhibition of Carnitine Palmitoyltransferase-1 Activity Alleviates Insulin Resistance in Diet-Induced Obese Mice
por: Keung, Wendy, et al.
Publicado: (2013)

Carnitine Palmitoyltransferase 1b Deficiency Protects Mice from Diet-Induced Insulin Resistance
por: Kim, Teayoun, et al.
Publicado: (2014)

Recurrent rhabdomyolysis caused by carnitine palmitoyltransferase II deficiency, common but under-recognised: Lessons to be learnt
por: Balasubramanian, M., et al.
Publicado: (2018)

Endogenous genetic risk factor for serious heatstroke: the thermolabile phenotype of carnitine palmitoyltransferase II variant
por: Oda, Jun, et al.
Publicado: (2018)

Normal FGF-21-Serum Levels in Patients with Carnitine Palmitoyltransferase II (CPT II) Deficiency
por: Motlagh Scholle, Leila, et al.
Publicado: (2019)

A surviving 24-month-old patient with neonatal-onset carnitine palmitoyltransferase II deficiency
por: Ikeda, Naohiro, et al.
Publicado: (2017)

Evidence for an Association Between Infant Mortality and Homozygosity For the Arctic Variant of Carnitine Palmitoyltransferase 1A
por: Gessner, Bradford D., et al.
Publicado: (2016)

Identification and Characterization of Carnitine Palmitoyltransferase 1 (cpt 1) Genes in Nile Tilapia, Oreochromis niloticus
por: Bayır, Mehtap, et al.
Publicado: (2020)

Lipidomics reveals carnitine palmitoyltransferase 1C protects cancer cells from lipotoxicity and senescence
por: Zhang, Huizhen, et al.
Publicado: (2021)

Carnitine palmitoyltransferase gene upregulation by linoleic acid induces CD4(+) T cell apoptosis promoting HCC development
por: Brown, Zachary J., et al.
Publicado: (2018)

miR-9 upregulation leads to inhibition of erythropoiesis by repressing FoxO3
por: Zhang, Yunyuan, et al.
Publicado: (2018)

Carnitine Palmitoyltransferase 1 Increases Lipolysis, UCP1 Protein Expression and Mitochondrial Activity in Brown Adipocytes
por: Calderon-Dominguez, María, et al.
Publicado: (2016)

Upregulating carnitine palmitoyltransferase 1 attenuates hyperoxia-induced endothelial cell dysfunction and persistent lung injury
por: Chang, Jason L., et al.
Publicado: (2022)

The impact of variance in carnitine palmitoyltransferase-1 expression on breast cancer prognosis is stratified by clinical and anthropometric factors
por: Liu, Ryan, et al.
Publicado: (2023)

The Reversible Carnitine Palmitoyltransferase 1 Inhibitor (Teglicar) Ameliorates the Neurodegenerative Phenotype in a Drosophila Huntington’s Disease Model by Acting on the Expression of Carnitine-Related Genes
por: Bertapelle, Carla, et al.
Publicado: (2022)

ApoE4 attenuates autophagy via FoxO3a repression in the brain
por: Sohn, Hee-Young, et al.
Publicado: (2021)

Apigenin Attenuates Acetaminophen-Induced Hepatotoxicity by Activating AMP-Activated Protein Kinase/Carnitine Palmitoyltransferase I Pathway
por: Zhang, Jiaqi, et al.
Publicado: (2020)

Carnitine palmitoyltransferase 1C negatively regulates the endocannabinoid hydrolase ABHD6 in mice, depending on nutritional status
por: Miralpeix, Cristina, et al.
Publicado: (2021)

Mitochondrial carnitine palmitoyltransferase-II dysfunction: A possible novel mechanism for nonalcoholic fatty liver disease in hepatocarcinogenesis
por: Yao, Min, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_nmab4s9i0rdr0r3q0082rsn3o3