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Identification of H7 as a novel peroxiredoxin I inhibitor to induce differentiation of leukemia cells

Identifying novel targets to enhance leukemia-cell differentiation is an urgent requirment. We have recently proposed that inhibiting the antioxidant enzyme peroxiredoxin I (Prdx I) may induce leukemia-cell differentiation. However, this concept remains to be confirmed. In this work, we identified H...

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Detalles Bibliográficos
Autores principales: Wei, Wei, Ma, Chunmin, Cao, Yang, Yang, Li, Huang, Zhimin, Qin, Dongjun, Chen, Yingyi, Liu, Chuanxu, Xia, Li, Wang, Tongdan, Lei, Hu, Yu, Yun, Huang, Min, Tong, Yin, Xu, Hanzhang, Gao, Fenghou, Zhang, Jian, Wu, Ying-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826176/
https://www.ncbi.nlm.nih.gov/pubmed/26716647
http://dx.doi.org/10.18632/oncotarget.6763