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Loss of E-cadherin disrupts ovarian epithelial inclusion cyst formation and collective cell movement in ovarian cancer cells

Increased inclusion cyst formation in the ovary is associated with ovarian cancer development. We employed in vitro three-dimensional (3D) organotypic models formed by normal human ovarian surface epithelial (OSE) cells and ovarian cancer cells to study the morphologies of normal and cancerous ovari...

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Detalles Bibliográficos
Autores principales: Choi, Pui-Wah, Yang, Junzheng, Ng, Shu-Kay, Feltmate, Colleen, Muto, Michael G., Hasselblatt, Kathleen, Lafferty-Whyte, Kyle, JeBailey, Lellean, MacConaill, Laura, Welch, William R., Fong, Wing-Ping, Berkowitz, Ross S., Ng, Shu-Wing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826193/
https://www.ncbi.nlm.nih.gov/pubmed/26684027
http://dx.doi.org/10.18632/oncotarget.6588