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RASSF10 is an epigenetically inactivated tumor suppressor and independent prognostic factor in hepatocellular carcinoma

Methylation of the Ras-association domain family 10 (RASSF10) promoter region correlates with clinicopathological characteristics and poor prognosis in several human cancers. Here, we examined RASSF10 expression in hepatocellular carcinoma (HCC) and its role in hepatocarcinogenesis. RASSF10 mRNA and...

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Detalles Bibliográficos
Autores principales: Wang, Fei, Feng, Ying, Li, Peng, Wang, Kun, Feng, Liang, Liu, Yi-Fei, Huang, Hua, Guo, Yi-Bing, Mao, Qin-Sheng, Xue, Wan-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826205/
https://www.ncbi.nlm.nih.gov/pubmed/26701853
http://dx.doi.org/10.18632/oncotarget.6654