WWOX modulates the ATR-mediated DNA damage checkpoint response

For many decades genomic instability is considered one of the hallmarks of cancer. Role of the tumor suppressor WWOX (WW domain-containing oxidoreductase) in DNA damage response upon double strand breaks has been recently revealed. Here we demonstrate unforeseen functions for WWOX upon DNA single st...

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Detalles Bibliográficos
Autores principales: Abu-Odeh, Mohammad, Hereema, Nyla A., Aqeilan, Rami I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826209/
https://www.ncbi.nlm.nih.gov/pubmed/26675548
http://dx.doi.org/10.18632/oncotarget.6571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826209/
https://www.ncbi.nlm.nih.gov/pubmed/26675548
http://dx.doi.org/10.18632/oncotarget.6571

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