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WWOX modulates the ATR-mediated DNA damage checkpoint response

For many decades genomic instability is considered one of the hallmarks of cancer. Role of the tumor suppressor WWOX (WW domain-containing oxidoreductase) in DNA damage response upon double strand breaks has been recently revealed. Here we demonstrate unforeseen functions for WWOX upon DNA single st...

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Detalles Bibliográficos
Autores principales:	Abu-Odeh, Mohammad, Hereema, Nyla A., Aqeilan, Rami I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826209/ https://www.ncbi.nlm.nih.gov/pubmed/26675548 http://dx.doi.org/10.18632/oncotarget.6571

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