Cargando…

Adenovirus-mediated delivery of herpes simplex virus thymidine kinase administration improves outcome of recurrent high-grade glioma

BACKGROUND: This randomized, open-label, multicenter, phase II clinical trial was conducted to assess the anti-tumor efficacy and safety of replication-deficient adenovirus mutant thymidine kinase (ADV-TK) in combination with ganciclovir administration in patients with recurrent high-grade glioma (H...

Descripción completa

Detalles Bibliográficos
Autores principales: Ji, Nan, Weng, Danhui, Liu, Cang, Gu, Zheng, Chen, Shizhang, Guo, Ying, Fan, Zhong, Wang, Xiao, Chen, Jianfei, Zhao, Yanyan, Zhou, Jianfeng, Wang, Jisheng, Ma, Ding, Li, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826211/
https://www.ncbi.nlm.nih.gov/pubmed/26716896
http://dx.doi.org/10.18632/oncotarget.6737