Sildenafil (Viagra) sensitizes prostate cancer cells to doxorubicin-mediated apoptosis through CD95

We previously reported that Sildenafil enhances apoptosis and antitumor efficacy of doxorubicin (DOX) while attenuating its cardiotoxic effect in prostate cancer. In the present study, we investigated the mechanism by which sildenafil sensitizes DOX in killing of prostate cancer (PCa) cells, DU145....

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Detalles Bibliográficos
Autores principales: Das, Anindita, Durrant, David, Mitchell, Clint, Dent, Paul, Batra, Surinder K., Kukreja, Rakesh C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826214/
https://www.ncbi.nlm.nih.gov/pubmed/26716643
http://dx.doi.org/10.18632/oncotarget.6749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826214/
https://www.ncbi.nlm.nih.gov/pubmed/26716643
http://dx.doi.org/10.18632/oncotarget.6749

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