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Sildenafil (Viagra) sensitizes prostate cancer cells to doxorubicin-mediated apoptosis through CD95
We previously reported that Sildenafil enhances apoptosis and antitumor efficacy of doxorubicin (DOX) while attenuating its cardiotoxic effect in prostate cancer. In the present study, we investigated the mechanism by which sildenafil sensitizes DOX in killing of prostate cancer (PCa) cells, DU145....
Autores principales: | Das, Anindita, Durrant, David, Mitchell, Clint, Dent, Paul, Batra, Surinder K., Kukreja, Rakesh C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826214/ https://www.ncbi.nlm.nih.gov/pubmed/26716643 http://dx.doi.org/10.18632/oncotarget.6749 |
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