Induction of MAPK- and ROS-dependent autophagy and apoptosis in gastric carcinoma by combination of romidepsin and bortezomib

Proteasome inhibitors and histone deacetylase (HDAC) inhibitors can synergistically induce apoptotic cell death in certain cancer cell types but their combinatorial effect on the induction of autophagy remains unknown. Here, we investigated the combinatorial effects of a proteasome inhibitor, bortez...

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Detalles Bibliográficos
Autores principales: Hui, Kwai Fung, Yeung, Po Ling, Chiang, Alan K.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826218/
https://www.ncbi.nlm.nih.gov/pubmed/26683357
http://dx.doi.org/10.18632/oncotarget.6601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826218/
https://www.ncbi.nlm.nih.gov/pubmed/26683357
http://dx.doi.org/10.18632/oncotarget.6601

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