Galiellalactone induces cell cycle arrest and apoptosis through the ATM/ATR pathway in prostate cancer cells

Galiellalactone (GL) is a fungal metabolite that presents antitumor activities on prostate cancer in vitro and in vivo. In this study we show that GL induced cell cycle arrest in G(2)/M phase, caspase-dependent apoptosis and also affected the microtubule organization and migration ability in DU145 c...

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Detalles Bibliográficos
Autores principales: García, Víctor, Lara-Chica, Maribel, Cantarero, Irene, Sterner, Olov, Calzado, Marco A., Muñoz, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826221/
https://www.ncbi.nlm.nih.gov/pubmed/26683224
http://dx.doi.org/10.18632/oncotarget.6606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826221/
https://www.ncbi.nlm.nih.gov/pubmed/26683224
http://dx.doi.org/10.18632/oncotarget.6606

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