Identification of TIM3 2′-fluoro oligonucleotide aptamer by HT-SELEX for cancer immunotherapy

TIM3 belongs to a family of receptors that are involved in T-cell exhaustion and Treg functions. The development of new therapeutic agents to block this type of receptors is opening a new avenue in cancer immunotherapy. There are currently several clinical trials ongoing to combine different immune-...

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Detalles Bibliográficos
Autores principales: Hervas-Stubbs, Sandra, Soldevilla, Mario M., Villanueva, Helena, Mancheño, Uxua, Bendandi, Maurizio, Pastor, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826223/
https://www.ncbi.nlm.nih.gov/pubmed/26683225
http://dx.doi.org/10.18632/oncotarget.6608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826223/
https://www.ncbi.nlm.nih.gov/pubmed/26683225
http://dx.doi.org/10.18632/oncotarget.6608

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