Deep sequencing of uveal melanoma identifies a recurrent mutation in PLCB4

Next generation sequencing of uveal melanoma (UM) samples has identified a number of recurrent oncogenic or loss-of-function mutations in key driver genes including: GNAQ, GNA11, EIF1AX, SF3B1 and BAP1. To search for additional driver mutations in this tumor type we carried out whole-genome or whole...

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Detalles Bibliográficos
Autores principales: Johansson, Peter, Aoude, Lauren G., Wadt, Karin, Glasson, William J., Warrier, Sunil K., Hewitt, Alex W., Kiilgaard, Jens Folke, Heegaard, Steffen, Isaacs, Tim, Franchina, Maria, Ingvar, Christian, Vermeulen, Tersia, Whitehead, Kevin J., Schmidt, Christopher W., Palmer, Jane M., Symmons, Judith, Gerdes, Anne-Marie, Jönsson, Göran, Hayward, Nicholas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826231/
https://www.ncbi.nlm.nih.gov/pubmed/26683228
http://dx.doi.org/10.18632/oncotarget.6614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826231/
https://www.ncbi.nlm.nih.gov/pubmed/26683228
http://dx.doi.org/10.18632/oncotarget.6614

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