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Regulation of the epithelial to mesenchymal transition and metastasis by Raf kinase inhibitory protein-dependent Notch1 activity

Raf kinase inhibitory protein (RKIP), an endogenous inhibitor of the extracellular signal-regulated kinase (ERK) pathway, has been implicated as a suppressor of metastasis and a prognostic marker in cancers. However, how RKIP acts as a suppressor during metastasis is not fully understood. Here, we s...

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Detalles Bibliográficos
Autores principales: Noh, Hae Sook, Hah, Young-Sool, Ha, Ji Hye, Kang, Min Young, Zada, Sahib, Rha, Sun Young, Kang, Sang Soo, Kim, Hyun Joon, Park, Jae-Yong, Byun, June-Ho, Hahm, Jong Ryeal, Shin, Jeong Kyu, Jeong, Sang-Ho, Lee, Young-Joon, Kim, Deok Ryong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826232/
https://www.ncbi.nlm.nih.gov/pubmed/26716415
http://dx.doi.org/10.18632/oncotarget.6728