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MicroRNA-1225-5p inhibits proliferation and metastasis of gastric carcinoma through repressing insulin receptor substrate-1 and activation of β-catenin signaling

Emerging evidence has linked aberrantly expressed microRNAs (miRNAs) with oncogenesis and malignant development in various human cancers. However, their specific roles and functions in gastric carcinoma (GC) remain largely undefined. In this study we identify and report a novel miRNA, miR-1225-5p, a...

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Detalles Bibliográficos
Autores principales: Zheng, Haiyin, Zhang, Fuxing, Lin, Xinjian, Huang, Changming, Zhang, Yiqin, Li, Yun, Lin, Jianyin, Chen, Wannan, Lin, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826233/
https://www.ncbi.nlm.nih.gov/pubmed/26684358
http://dx.doi.org/10.18632/oncotarget.6615