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PKCδ activated by c-MET enhances infiltration of human glioblastoma cells through NOTCH2 signaling

Poor prognosis of glioblastoma (GBM) is attributable to the propensity of tumor cells to infiltrate into the brain parenchyma. Protein kinase C (PKC) isozymes are highly expressed or aberrantly activated in GBM. However, how this signaling node translates to GBM cell invasiveness remains unknown. He...

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Detalles Bibliográficos
Autores principales: Hwang, Eunji, Yoo, Ki-Chun, Kang, Seok-Gu, Kim, Rae-Kwon, Cui, Yan-Hong, Lee, Hae-June, Kim, Min-Jung, Lee, Jae-Seong, Kim, In-Gyu, Suh, Yongjoon, Lee, Su-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826251/
https://www.ncbi.nlm.nih.gov/pubmed/26700818
http://dx.doi.org/10.18632/oncotarget.6640