Cell cycle-dependent resolution of DNA double-strand breaks

DNA double strand breaks (DSBs) elicit prompt activation of DNA damage response (DDR), which arrests cell-cycle either in G(1)/S or G(2)/M in order to avoid entering S and M phase with damaged DNAs. Since mammalian tissues contain both proliferating and quiescent cells, there might be fundamental di...

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Detalles Bibliográficos
Autores principales: Ambrosio, Susanna, Di Palo, Giacomo, Napolitano, Giuliana, Amente, Stefano, Dellino, Gaetano Ivan, Faretta, Mario, Pelicci, Pier Giuseppe, Lania, Luigi, Majello, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826256/
https://www.ncbi.nlm.nih.gov/pubmed/26700820
http://dx.doi.org/10.18632/oncotarget.6644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826256/
https://www.ncbi.nlm.nih.gov/pubmed/26700820
http://dx.doi.org/10.18632/oncotarget.6644

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