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The drug target genes show higher evolutionary conservation than non-target genes

Although evidence indicates that drug target genes share some common evolutionary features, there have been few studies analyzing evolutionary features of drug targets from an overall level. Therefore, we conducted an analysis which aimed to investigate the evolutionary characteristics of drug targe...

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Detalles Bibliográficos
Autores principales: Lv, Wenhua, Xu, Yongdeng, Guo, Yiying, Yu, Ziqi, Feng, Guanglong, Liu, Panpan, Luan, Meiwei, Zhu, Hongjie, Liu, Guiyou, Zhang, Mingming, Lv, Hongchao, Duan, Lian, Shang, Zhenwei, Li, Jin, Jiang, Yongshuai, Zhang, Ruijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826257/
https://www.ncbi.nlm.nih.gov/pubmed/26716901
http://dx.doi.org/10.18632/oncotarget.6755