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New Structural Insights into the Genome and Minor Capsid Proteins of BK Polyomavirus using Cryo-Electron Microscopy

BK polyomavirus is the causative agent of several diseases in transplant patients and the immunosuppressed. In order to better understand the structure and life cycle of BK, we produced infectious virions and VP1-only virus-like particles in cell culture, and determined their three-dimensional struc...

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Detalles Bibliográficos
Autores principales: Hurdiss, Daniel L., Morgan, Ethan L., Thompson, Rebecca F., Prescott, Emma L., Panou, Margarita M., Macdonald, Andrew, Ranson, Neil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826271/
https://www.ncbi.nlm.nih.gov/pubmed/26996963
http://dx.doi.org/10.1016/j.str.2016.02.008