Cellular 5′-3′ mRNA Exonuclease Xrn1 Controls Double-Stranded RNA Accumulation and Anti-Viral Responses

By accelerating global mRNA decay, many viruses impair host protein synthesis, limiting host defenses and stimulating virus mRNA translation. Vaccinia virus (VacV) encodes two decapping enzymes (D9, D10) that remove protective 5′ caps on mRNAs, presumably generating substrates for degradation by the...

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Detalles Bibliográficos
Autores principales: Burgess, Hannah M., Mohr, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826345/
https://www.ncbi.nlm.nih.gov/pubmed/25766294
http://dx.doi.org/10.1016/j.chom.2015.02.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826345/
https://www.ncbi.nlm.nih.gov/pubmed/25766294
http://dx.doi.org/10.1016/j.chom.2015.02.003

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