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Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model

Autophagy is an evolutionarily conserved cellular process controlled through a set of essential autophagy genes (Atgs). However, there is increasing evidence that most, if not all, Atgs also possess functions independent of their requirement in canonical autophagy, making it difficult to distinguish...

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Detalles Bibliográficos
Autores principales: Chen, Song, Wang, Chenran, Yeo, Syn, Liang, Chun-Chi, Okamoto, Takako, Sun, Shaogang, Wen, Jian, Guan, Jun-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826400/
https://www.ncbi.nlm.nih.gov/pubmed/27013233
http://dx.doi.org/10.1101/gad.276428.115