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Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model
Autophagy is an evolutionarily conserved cellular process controlled through a set of essential autophagy genes (Atgs). However, there is increasing evidence that most, if not all, Atgs also possess functions independent of their requirement in canonical autophagy, making it difficult to distinguish...
Autores principales: | Chen, Song, Wang, Chenran, Yeo, Syn, Liang, Chun-Chi, Okamoto, Takako, Sun, Shaogang, Wen, Jian, Guan, Jun-Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826400/ https://www.ncbi.nlm.nih.gov/pubmed/27013233 http://dx.doi.org/10.1101/gad.276428.115 |
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