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A beneficial tumor microenvironment in oropharyngeal squamous cell carcinoma is characterized by a high T cell and low IL-17(+) cell frequency

Patients with HPV-positive oropharyngeal squamous cell carcinomas (OPSCCs) have a better prognosis than patients with non-HPV-induced OPSCC. The role of the immune response in this phenomenon is yet unclear. We studied the number of T cells, regulatory T cells (Tregs), T helper 17 (Th17) cells and I...

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Detalles Bibliográficos
Autores principales: Punt, Simone, Dronkers, Emilie A. C., Welters, Marij J. P., Goedemans, Renske, Koljenović, Senada, Bloemena, Elisabeth, Snijders, Peter J. F., Gorter, Arko, van der Burg, Sjoerd H., de Jong, Robert J. Baatenburg, Jordanova, Ekaterina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826411/
https://www.ncbi.nlm.nih.gov/pubmed/26899388
http://dx.doi.org/10.1007/s00262-016-1805-x