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More than just trash bins? Potential roles for extracellular vesicles in the vertical and horizontal transmission of yeast prions

In the yeast Saccharomyces cerevisiae, an ensemble of structurally and functionally diverse cytoplasmic proteins has the ability to form self-perpetuating protein aggregates (e.g. prions) which are the vectors of heritable non-Mendelian phenotypic traits. Whether harboring these prions is deleteriou...

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Detalles Bibliográficos
Autores principales: Kabani, Mehdi, Melki, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826420/
https://www.ncbi.nlm.nih.gov/pubmed/26553335
http://dx.doi.org/10.1007/s00294-015-0534-6