Decoration of intramyocellular lipid droplets with PLIN5 modulates fasting-induced insulin resistance and lipotoxicity in humans

AIMS/HYPOTHESIS: In contrast to insulin-resistant individuals, insulin-sensitive athletes possess high intramyocellular lipid content (IMCL), good mitochondrial function and high perilipin 5 (PLIN5) levels, suggesting a role for PLIN5 in benign IMCL storage. We hypothesised a role for PLIN5 in modul...

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Detalles Bibliográficos
Autores principales: Gemmink, Anne, Bosma, Madeleen, Kuijpers, Helma J. H., Hoeks, Joris, Schaart, Gert, van Zandvoort, Marc A. M. J., Schrauwen, Patrick, Hesselink, Matthijs K. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826431/
https://www.ncbi.nlm.nih.gov/pubmed/26864436
http://dx.doi.org/10.1007/s00125-016-3865-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826431/
https://www.ncbi.nlm.nih.gov/pubmed/26864436
http://dx.doi.org/10.1007/s00125-016-3865-z

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