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Pak4 Is Required during Epithelial Polarity Remodeling through Regulating AJ Stability and Bazooka Retention at the ZA

The ability of epithelial cells to assemble into sheets relies on their zonula adherens (ZA), a circumferential belt of adherens junction (AJ) material, which can be remodeled during development to shape organs. Here, we show that during ZA remodeling in a model neuroepithelial cell, the Cdc42 effec...

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Detalles Bibliográficos
Autores principales: Walther, Rhian F., Nunes de Almeida, Francisca, Vlassaks, Evi, Burden, Jemima J., Pichaud, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826445/
https://www.ncbi.nlm.nih.gov/pubmed/27052178
http://dx.doi.org/10.1016/j.celrep.2016.03.014