Cargando…

2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size

Variation in cerebral cortex size and complexity is thought to contribute to differences in cognitive ability between humans and other animals. Here we compare cortical progenitor cell output in humans and three nonhuman primates using directed differentiation of pluripotent stem cells (PSCs) in adh...

Descripción completa

Detalles Bibliográficos
Autores principales: Otani, Tomoki, Marchetto, Maria C., Gage, Fred H., Simons, Benjamin D., Livesey, Frederick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826446/
https://www.ncbi.nlm.nih.gov/pubmed/27049876
http://dx.doi.org/10.1016/j.stem.2016.03.003