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The inhibition of microRNAs by HIV-1 Tat suppresses beta catenin activity in astrocytes
BACKGROUND: Long term infection with HIV-1, even in the context of therapy, leads to chronic health problems including an array of neurocognitive dysfunctions. The viral Tat protein has previously been implicated in neuropathogenesis through its effect on astrocytes. Tat has also been shown to inhib...
Autores principales: | Sardo, Luca, Vakil, Priyal R., Elbezanti, Weam, El-Sayed, Anas, Klase, Zachary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826512/ https://www.ncbi.nlm.nih.gov/pubmed/27060080 http://dx.doi.org/10.1186/s12977-016-0256-y |
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