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Randomized phase III trial of amrubicin/cisplatin versus etoposide/cisplatin as first-line treatment for extensive small-cell lung cancer

BACKGROUND: Extensive-disease small-cell lung cancer (ED-SCLC) is characterized by rapid progression and relapse, despite high initial response rates to chemotherapy. The primary objective of this trial was to demonstrate the non-inferiority of amrubicin and cisplatin (AP) combination therapy compar...

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Detalles Bibliográficos
Autores principales: Sun, Yan, Cheng, Ying, Hao, Xuezhi, Wang, Jie, Hu, Chengping, Han, Baohui, Liu, Xiaoqing, Zhang, Li, Wan, Huiping, Xia, Zhongjun, Liu, Yunpeng, Li, Wei, Hou, Mei, Zhang, Helong, Xiu, Qingyu, Zhu, Yunzhong, Feng, Jifeng, Qin, Shukui, Luo, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826513/
https://www.ncbi.nlm.nih.gov/pubmed/27061082
http://dx.doi.org/10.1186/s12885-016-2301-6