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Brain-targeted delivery of resveratrol using solid lipid nanoparticles functionalized with apolipoprotein E

BACKGROUND: The present study takes advantage of the beneficial effects of resveratrol as a neuroprotective compound. Resveratrol-loaded solid lipid nanoparticles were functionalized with apolipoprotein E which can be recognized by the LDL receptors overexpressed on the blood–brain barrier. RESULTS:...

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Detalles Bibliográficos
Autores principales: Neves, Ana Rute, Queiroz, Joana Fontes, Reis, Salette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826547/
https://www.ncbi.nlm.nih.gov/pubmed/27061902
http://dx.doi.org/10.1186/s12951-016-0177-x