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Brain-targeted delivery of resveratrol using solid lipid nanoparticles functionalized with apolipoprotein E
BACKGROUND: The present study takes advantage of the beneficial effects of resveratrol as a neuroprotective compound. Resveratrol-loaded solid lipid nanoparticles were functionalized with apolipoprotein E which can be recognized by the LDL receptors overexpressed on the blood–brain barrier. RESULTS:...
Autores principales: | Neves, Ana Rute, Queiroz, Joana Fontes, Reis, Salette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826547/ https://www.ncbi.nlm.nih.gov/pubmed/27061902 http://dx.doi.org/10.1186/s12951-016-0177-x |
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