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SENP1-Mediated Desumoylation of DBC1 Inhibits Apoptosis Induced by High Glucose in Bovine Retinal Pericytes

Pericyte loss is an early characteristic change in diabetic retinopathy, but its precise molecular mechanisms have not been elucidated. This study investigated the role of SENP1 in pericyte loss in diabetic retinopathy. We demonstrated that a high concentration of glucose inhibited the expression of...

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Detalles Bibliográficos
Autores principales: Gao, Jian, Chen, Xia, Gu, Qing, Liu, Xiaoxiao, Xu, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826714/
https://www.ncbi.nlm.nih.gov/pubmed/27110392
http://dx.doi.org/10.1155/2016/6392658