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Complementary activities of TPX2 and chTOG constitute an efficient importin-regulated microtubule nucleation module

Spindle assembly and function require precise control of microtubule nucleation and dynamics. The chromatin-driven spindle assembly pathway exerts such control locally in the vicinity of chromosomes. One of the key targets of this pathway is TPX2. The molecular mechanism of how TPX2 stimulates micro...

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Detalles Bibliográficos
Autores principales: Roostalu, Johanna, Cade, Nicholas I., Surrey, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826748/
https://www.ncbi.nlm.nih.gov/pubmed/26414402
http://dx.doi.org/10.1038/ncb3241