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(2R,3S,2”R,3”R)-manniflavanone, a new gastrointestinal smooth muscle L-type calcium channel inhibitor, which underlies the spasmolytic properties of Garcinia buchananii stem bark extract

Garcinia buchananii Baker stem bark extract (GBB) is a traditional medication of diarrhea and dysentery in sub-Saharan Africa. It is believed that GBB causes gastrointestinal smooth muscle relaxation. The aim of this study was to determine whether GBB has spasmolytic actions and identify compounds u...

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Detalles Bibliográficos
Autores principales: Balemba, Onesmo B., Stark, Timo D., Lösch, Sofie, Patterson, Savannah, McMillan, John S., Mawe, Gary M., Hofmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Society of Smooth Muscle Research 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826780/
https://www.ncbi.nlm.nih.gov/pubmed/26081368
http://dx.doi.org/10.1540/jsmr.50.48